Streams draining agricultural landscapes may receive significant inputs of crop detritus, including transgenic materials containing Bacillus thuringiensis (Bt) δ-endotoxin proteins. However, potential influences of these materials on stream invertebrate communities have received little attention. We quantified crop detritus inputs to streams draining both Bt and traditional corn fields in Indiana and assessed potential impacts on macroinvertebrates using quantitative field sampling, litterbag studies, and laboratory feeding trials. Crop detritus comprised up to 40% of allochthonous litter entering these streams during fall harvest. Laboratory experiments showed that Lepidostoma, trichopterans that are related to the lepidopteran targets of Bt toxins, grew slower when fed Bt corn (instantaneous growth = 0.022 d^-1) compared to traditional corn (0.049 d^-1) (p=0.049). However, trichopteran biomass and total shredder biomass was similar in Bt and traditional corn litterbags, and there was no difference in decay rates of Bt and traditional corn litter. Macroinvertebrate communities were similar between the two stream types, and trichopterans were poorly represented in all streams (1% of total biomass). Results demonstrate that Bt corn detritus can slow growth of shredding caddisflies, but in situ it did not have significant adverse effects on invertebrates in these highly degraded streams.