Pacific salmon (Oncorhynchus spp.) are known to be a source of significant resource subsidies and sediment disturbance to Northern Pacific rim watersheds.  Fisheries and timber harvest constitute a dual impact on the complex ecological relationships between salmon spawners and coupled terrestrial-freshwater ecosystems.  We studied how timber harvest can modify such relationships by evaluating the ecological responses to spawners in stream and riparian habitats of several watersheds on Prince of Wales Island, southeastern Alaska.  These watersheds receive a range of salmon spawner densities (0.01-0.14 fish per m²) and have been subject to different intensities of timber harvest (6-85% watershed harvested).  Considerable heterogeneity exists in the physical (e.g., substrate size 32-118 mm), chemical (e.g., soluble reactive phosphorus 2-5 µg L^-1), and biological (e.g., 3-14 mg chlorophyll a m²) conditions associated with these watersheds. However, such heterogeneity did not mask a dampening of ecological responses to spawners with increased intensity of timber harvest.  We have combined field and GIS data to develop a conceptual framework with which resource managers could make spatially and temporally explicit decisions about timber harvest.  Such a framework will ideally allow timber harvest across a heterogeneous landscape without compromising the capacity of watersheds to retain and utilize spawner resources.